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pentobarbital will minimize the level or impact of larotrectinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lower the extent or outcome of ixabepilone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will reduce the extent or result of verapamil by influencing hepatic/intesti